Oraqix is composed of which two anesthetics?

Oraqix is composed of which two anesthetics?

• A. Lidocaine and Prilocaine
• B. Lidocaine and Mepivacaine
• C. Prilocaine and Tetracaine
• D. Benzocaine and Prilocaine

Answer: (A)

Oraqix is a topical gel used to numb periodontal tissues, and it is made from two amide local anesthetics: lidocaine and prilocaine. The combination is chosen because lidocaine provides a rapid onset of numbness, while prilocaine contributes a longer duration of anesthesia. Together they block voltage-gated sodium channels in nerve membranes, preventing nerve impulses from being sent and producing localized numbness in the gingival tissues without the need for injections. The low concentrations help keep systemic absorption to a minimum for safety in the confined periodontal pocket. The other possible combinations involve different anesthetics or types (such as esters) and are not the formulation used in Oraqix.

Oraqix is a topical gel used to numb periodontal tissues, and it is made from two amide local anesthetics: lidocaine and prilocaine. The combination is chosen because lidocaine provides a rapid onset of numbness, while prilocaine contributes a longer duration of anesthesia. Together they block voltage-gated sodium channels in nerve membranes, preventing nerve impulses from being sent and producing localized numbness in the gingival tissues without the need for injections. The low concentrations help keep systemic absorption to a minimum for safety in the confined periodontal pocket. The other possible combinations involve different anesthetics or types (such as esters) and are not the formulation used in Oraqix.