Which local anesthetic formulation is the only one available with levonordefrin?

Which local anesthetic formulation is the only one available with levonordefrin?

• A. 2% mepivacine
• B. Lidocaine with levonordefrin
• C. Prilocaine with levonordefrin
• D. Articaine with levonordefrin

Answer: (A)

Levonordefrin is a vasoconstrictor used with certain local anesthetics to narrow blood vessels, which helps keep the drug localized and prolongs anesthesia while reducing systemic spread. In dental practice, formulations containing levonordefrin are limited to the mepivacaine base, typically sold as a 2% solution with levonordefrin (often at a 1:20,000 dilution). Other commonly used local anesthetics, such as lidocaine, prilocaine, and articaine, are usually paired with epinephrine as the vasoconstrictor rather than levonordefrin. Because of this, the only formulation among the options that contains levonordefrin is the 2% mepivacaine formulation.

Levonordefrin is a vasoconstrictor used with certain local anesthetics to narrow blood vessels, which helps keep the drug localized and prolongs anesthesia while reducing systemic spread. In dental practice, formulations containing levonordefrin are limited to the mepivacaine base, typically sold as a 2% solution with levonordefrin (often at a 1:20,000 dilution). Other commonly used local anesthetics, such as lidocaine, prilocaine, and articaine, are usually paired with epinephrine as the vasoconstrictor rather than levonordefrin. Because of this, the only formulation among the options that contains levonordefrin is the 2% mepivacaine formulation.